Nanotech 2016: SMALP Conference

Membrane Protein Nanoparticle Solutions

Location: Hart House Music Room, University of Toronto, Canada

Date: April 29, 2016

Timetable: Workshop from 8:00am and meeting from 9:00am - 5:00pm

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Oliver Ernst, Professor and Head of Structural Neurobiology Lab, University of Toronto, studies the structural basis of transmembrane signaling by GPCRs and rhodopsins by spectroscopic and X-ray crystallographic techniques.


Jana Broecker, Postdoctoral DFG Fellow, Structural Neurobiology Lab, University of Toronto on comparison of SMALP and detergent based membrane protein crystallization and structure determination

Tim Dafforn, Professor of Biotechnology at the University of Birmingham and Chief Scientific Adviser at the Department for Business, Innovation and Skills, champion of synthetic biology and SMALP technology

Jonas Doerr, Utrecht University, is studying applications of SMA copolymers in membrane research and the detergent-free isolation of membrane proteins native lipids

Franck Duong, Associate Professor Biochemistry and Molecular Biology Faculty of Medicine, UBC on using nanodiscs and SMA to study the SecY complex (or translocon), which transports proteins into or across the bacterial membrane.

Sandro_KellerSandro Keller, Professor of Molecular Biophysics, Faculty of Biology, University of Kaiserslautern, Germany will present the biophysics of SMALP formation

Tom Laursen is a Post Doctoral Researcher studying membrane bound proteins in SMALPs and nanodiscs at the Joint BioEnergy Institute, USA, and studied plant biochemistry at the University of Copenhagen.

Gary Lorigan, Professor, Department of Chemistry and Biochemistry, Miami University, is studying lipodisq nanoparticles using different lipids via solid-state nuclear magnetic resonance spectroscopy and dynamic light scattering.

Chris Marshall is a Research Associate with Mitsu Ikura's group at the University of Toronto, and is using nanodiscs to study the structural biology, signaling and cancer mechanisms of Ras and Rho GTPase proteins

Michael Overduin, Professor, Department of Biochemistry, University of Alberta, co- developed the SMALP system and its collaborative community, and uses solution state NMR to characterize membrane proteins

Stefan Scheidelaar PhD researcher at Foundation for Fundamental Research on Matter, Utrecht University, Netherlands on SMALP Lipid Composition.



Glycon Biochemicals

Focus of the Meeting

This conference focuses on applications of polymer nanodiscs in membrane protein research. The talks will be held in the Music Room of Hart House in the University of Toronto, Canada.


8-8:45 Polymer Workshop
9-10:30 Synthesis/Biophysics
11-12:30 Membrane Proteins
1:30-3 Biological Mechanisms
3:30-5 Round Table Discussion

Lively discussion and debate will follow the talks, and continue over coffee breaks and lunch.

The practical workshop will allow best practice for polymer activation and use to be explored and disseminated.

Free polymer will be provided to workshop participants.

Contact us

Do let the organizers know if you have any questions by sending us your feedback.