Monica Spiteri
Professor Spiteri directs and oversees the Lung Research programme at the Research Institute for Science and Technology in Medicine at Keele University. This programme incorporates a multidisciplinary approach of cell pathology, molecular biology and bioengineering. She is developing near patient technologies for Chronic Obstructive Airways Disease with support from the National Institute of Health Research and NHS West Midlands Innovations.
Her group has established an international expertise in:
- Utilization of ex-vivo cell injury-repair models (incorporating appropriate mechanical stress stimuli) to explore mechanisms in tissue / airway wall remodelling in pulmonary fibrogenesis and rhinovirus-associated airway inflammation.
- Explorative technology for early detection and monitoring of lung disease. Specific areas of interest include :
- Use of optical coherence tomography for early detection of in situ precancerous / malignant lesions within the respiratory epithelium.
- Use of Fourier transform infrared spectroscopy for airway mucus analysis to identify individual health and disease onset-related sputum fingerprints.
